[Diagnosis of familial adenomatous polyposis based on DNA].

  • Michel Mego
  • Published 1998 in Bratislavske lekarske listy

Abstract

BACKGROUND Familial adenomatous polyposis is an autosomal dominant precancerous condition, characterized by the appearance of hundreds to thousands of colorectal polyps. Mutation of the APC gene located on 5q21-22 plays the major role in its etiology. OBJECTIVE Diagnoses and genetic prognosis of 7 persons of a family with previous case of FAP using… (More)

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