[Development of the mono-oxygenase system. Implications in perinatal pharmacotoxicology (author's transl)].


The hepatic or extra-hepatic mono-oxygenase activities ensure the metabolism of exogenic hydrophobic substances (xenobiotics) and endogenic substances (steroids). These substances easily cross the placenta ; it is of primary importance to know perfectly their possible transformation at the level of the foetus together with their excretion from the foetal… (More)


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