Corpus ID: 88866801

[Development of resistance to difuracil (PAP-49) in bacteria and its activity in combination with other antibacterial drugs].

@article{Pa1997DevelopmentOR,
  title={[Development of resistance to difuracil (PAP-49) in bacteria and its activity in combination with other antibacterial drugs].},
  author={Pavlov Pa},
  journal={Antibiotics and chemoterapy},
  year={1997},
  volume={42},
  pages={34}
}
  • Pavlov Pa
  • Published 1997
  • Chemistry
  • Antibiotics and chemoterapy
: Possible increasing of resistance to difuracil or N-(5-nitrofurfuryliden)-5-nitrofuran-2-(N'-acetyl) carboxamidohydrazon (PAP-49) in Staphylococcus sp., Streptococcus sp. and Escherichia coli was studied and the level of the resistance increasing was determined by the method of 30-fold passage of the cultures in subbacteriostatic concentrations of the drug. It was shown in vitro that the increase of the resistance to the new nitrofuran was insignificant. The most intensive adaptation was… Expand