[Development of murine models of ocular toxoplasmosis and preliminary results of ocular inflammatory transcriptome].

@article{Sauer2009DevelopmentOM,
  title={[Development of murine models of ocular toxoplasmosis and preliminary results of ocular inflammatory transcriptome].},
  author={Arnaud Sauer and Ibtissem Lahmar and Monika Scholler and Odile Villard and Claude Speeg-Schatz and Julie Brunet and Alexander Pfaff and Tristan M. Bourcier and Ermanno Candolfi},
  journal={Journal francais d'ophtalmologie},
  year={2009},
  volume={32 10},
  pages={742-9}
}
BACKGROUND/PURPOSE Toxoplasmosis is the most common cause of posterior uveitis in immunocompetent subjects. Taking into account the opposing needs of limiting parasite multiplication and minimizing tissue destruction, the infection imbalance most often involves CD4 and CD8 T lymphocytes that play the lead role in adaptive immunity to T. gondii. The aims of our study were to develop murine models of toxoplasmosis and to study the immune responses to the infection. METHODS Two murine models… CONTINUE READING