[Determination of risperidone and 9-hydroxyrisperidone in plasma by high performance liquid chromatography].

@article{Xiao1999DeterminationOR,
  title={[Determination of risperidone and 9-hydroxyrisperidone in plasma by high performance liquid chromatography].},
  author={Hong Xiao and Jun Yang and Shu-fen Zhang and Xiao-song Zhang},
  journal={Se pu = Chinese journal of chromatography},
  year={1999},
  volume={17 4},
  pages={395-6}
}
A reversed-phase HPLC method for the determination of risperidone and 9-hydroxyrisperidone in plasma was established. Risperidone and 9-hydroxyrisperidone can be separated on a Zorbax ODS C18 column with a mobile phase of MeOH-water-ammonium acetate (mol/L)-ammonia water(3 mol/L) (300:50:3:1, volume ratios) and detected at 280 nm. The flow rate was 0.8 mL… CONTINUE READING