[Detection and occurrence of BRCA 1 gene mutation in patients with carcinoma of the breast and ovary].


OBJECTIVE The article presents a review of basic information on incidence and detection of BRCA 1 and BRCA 2 genes mutations. Results of investigation in a group of women with ovarian and breast cancer are presented. DESIGN Retrospective clinical-laboratory study and review. SETTING Department of Gynaecology and Obstetrics, 1st Medical Faculty of… (More)


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