[Demonstration of the immunoreactivity of polynuclear eosinophils for bombesin and substance P. A new concept of the neuro-immune axis].

@article{Roland1996DemonstrationOT,
  title={[Demonstration of the immunoreactivity of polynuclear eosinophils for bombesin and substance P. A new concept of the neuro-immune axis].},
  author={Jean Claude Roland and Lydia Soranzo and Jean Marie Launay and B. Vargaftig},
  journal={Bulletin de l'Academie nationale de medecine},
  year={1996},
  volume={180 3},
  pages={
          697-706; discussion 706-8
        }
}
Immunoreactivity for B and SP was detected by means of light and electron microscopy (by preembedding immunocytochemistry), in eosiniphilic polymorphonuclear leukocytes infiltrating the connective tissue of gastrointestinal and respiratory tract in mouse, rat and human ; and in human bronchoalveolar lavages in case of hypereosinophilia. This positive reaction depends on the use of an acetic-acid-containing-fixative (minimum 48 hours), and is located in the granules of eosinophils at their… CONTINUE READING