[Demethylation of estrogen receptor gene and its re-expression in estrogen receptor-negative breast].


OBJECTIVE To investigate the correlation between the lack of estrogen receptor (ER) gene expression and hypermethylation of ER gene, and detect whether re-expressed ER protein is activated. METHODS The methylation status of ER gene promoter in the ER-negative breast cancer cells was evaluated by methylation specific PCR (MSP) and genomic sequencing. The… (More)



Citations per Year

Citation Velocity: 9

Averaging 9 citations per year over the last 3 years.

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