[Deguelin regulates cell cycle and nuclear pore complex protein Nup98 and Nup88 in U937 cells in vitro].

Abstract

OBJECTIVE To investigate antitumor activity and molecular mechanism of deguelin to the human U937 leukaemia cells and to explore the mechanisms regulating cell cycle and nucleoporin 98 (Nup98) and nucleoporin 88 (Nup88) in vitro. METHODS The effects of deguelin on the growth of U937 cells were studied by MTT assay, and the cell cycle of U937 cells by a… (More)

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