[Cytogenetic study on safety evaluation of human mesenchymal stem cells cultured in vitro].

@article{Matsuoka2010CytogeneticSO,
  title={[Cytogenetic study on safety evaluation of human mesenchymal stem cells cultured in vitro].},
  author={Atsuko Matsuoka},
  journal={Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences},
  year={2010},
  volume={128},
  pages={50-7}
}
  • Atsuko Matsuoka
  • Published 2010 in
    Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku…
Human mesenchymal stem cells (hMSCs) are one of the promising sources for regenerative medicine. In general, hMSCs are supposed to grow indefinitely and differentiate to various kinds of cells. The indefinite growth is concerned due to its misleading to carcinogenesis in the practical use of hMSCs in regenerative medicine. In the present study, we investigated unexpected changes, especially in genetic aspect, in hMSCs during culture utilizing fluorescence in situ hybridization (FISH) with… CONTINUE READING