[Cyclooxygenase-2 and cyclooxygenase-2 inhibitors in prostate cancer].

  title={[Cyclooxygenase-2 and cyclooxygenase-2 inhibitors in prostate cancer].},
  author={Song Xu and Jian-ping Gao and Wen-quan Zhou},
  journal={Zhonghua nan ke xue = National journal of andrology},
  volume={14 11},
Cyclooxygenase-2 (Cox-2) is over-expressed in prostate cancer (PCa) and involved in its development and progression by facilitating inflammatory response, reducing cell apoptosis, increasing angiogenesis and damaging DNA oxidation. Selective Cox-2 inhibitors suppress PCa growth through various channels and therefore have a promising application value in the… CONTINUE READING