[Cyclin D1, hTERT expression and telomerase activity in HL-60 and HL-60A cell lines and their significance].

@article{Huang2011CyclinDH,
  title={[Cyclin D1, hTERT expression and telomerase activity in HL-60 and HL-60A cell lines and their significance].},
  author={Ke-Zhi Huang and Da-nian Nie and Song-mei Yin and Yi-qing Li and Shuang-feng Xie and Li-ping Ma and Xiu-ju Wang and Yu-Dan Wu},
  journal={Zhongguo shi yan xue ye xue za zhi},
  year={2011},
  volume={19 4},
  pages={911-5}
}
To observe the expression of cyclin D1, hTERT, and telomerase activity in MNC, HL-60, HL-60A and to explore their effects on leukemogenesis and drug-resistance, normal human peripheral blood mononuclear cells, HL-60 cells sensitive to adriamycin and HL-60A cells resistant to adriamycin were investigated. The cell cycle was analyzed by flow cytometry, and the apoptosis was analyzed by Annexin V-FITC(+) PI staining. Expressions of cyclin D1 and hTERT were determined by real-time PCR and Western… CONTINUE READING

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