[Correlation of p73 polymorphisms to genetic susceptibilities to esophageal carcinoma and gastric cardiac carcinoma].

@article{Ge2006CorrelationOP,
  title={[Correlation of p73 polymorphisms to genetic susceptibilities to esophageal carcinoma and gastric cardiac carcinoma].},
  author={Hui Ge and Yi-min Wang and Yan-yan Cao and Xiu-feng Zhang and Yan Li and Wei Guo and Na Wang and Jianhui Zhang},
  journal={Ai zheng = Aizheng = Chinese journal of cancer},
  year={2006},
  volume={25 11},
  pages={
          1351-5
        }
}
BACKGROUND & OBJECTIVE p73 is a tumor suppressor gene. The two polymorphisms in the non-coding region of the exon 2 of p73 gene, named G4C14-A4T14, can form a stem-loop structure, and may influence p73 expression. This study was to investigate the correlation of p73 G4C14-A4T14 polymorphisms to susceptibilities to esophageal squamous cell carcinoma (ESCC) and gastric cardiac adenocarcinoma (GCA) in a high incidence region of Hebei Province. METHODS We conducted a population-based case-control… CONTINUE READING

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