Corpus ID: 37184034

[Contribution of electrophysiology to the study of tianeptine and other antidepressive agents].

@article{Dresse1991ContributionOE,
  title={[Contribution of electrophysiology to the study of tianeptine and other antidepressive agents].},
  author={A. Dresse and J. Scuv{\'e}e-Moreau and E. Mocaa{\"e}r and J. Poignant},
  journal={Presse medicale},
  year={1991},
  volume={20 37},
  pages={
          1807-11
        }
}
Intravenous perfusion of tianeptine reduces the frequency of coeruleus locus neural discharge. It does not affect the rate of neural discharge in the dorsal raphe, increase the rate of neural discharge in the ventral tegument air and the rate of discharge in the pyramidal cells of the hippocampus (CA1). In comparison, intravenous perfusion of clomipramine decreases the rate of neural discharge in the coeruleus locus, the dorsal raphe, the ventral tegument air (temporarily) and the pyramidal… Expand
1 Citations
Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity
TLDR
Tianeptine produces acute changes of electrocorticogram resembling rapid-acting antidepressants ketamine and N2O and may influence the magnitude of homeostatic emergence of delta-activity and TrkB-GSK3β signaling. Expand