Corpus ID: 37184034

[Contribution of electrophysiology to the study of tianeptine and other antidepressive agents].

@article{Dresse1991ContributionOE,
  title={[Contribution of electrophysiology to the study of tianeptine and other antidepressive agents].},
  author={A. Dresse and J. Scuv{\'e}e-Moreau and E. Mocaa{\"e}r and J. Poignant},
  journal={Presse medicale},
  year={1991},
  volume={20 37},
  pages={
          1807-11
        }
}
Intravenous perfusion of tianeptine reduces the frequency of coeruleus locus neural discharge. It does not affect the rate of neural discharge in the dorsal raphe, increase the rate of neural discharge in the ventral tegument air and the rate of discharge in the pyramidal cells of the hippocampus (CA1). In comparison, intravenous perfusion of clomipramine decreases the rate of neural discharge in the coeruleus locus, the dorsal raphe, the ventral tegument air (temporarily) and the pyramidal… Expand
1 Citations
Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity
BACKGROUND The precise mechanism governing the antidepressant effects of tianeptine is unknown. Modulation of brain glutamatergic neurotransmission has been however implicated, suggesting potentialExpand