[Construction of GSK-3beta-targeting RNAi adenovirus vector and the influence of Wnt/beta-catenin pathway in proliferation of human thyrocytes].

Abstract

OBJECTIVE To construct RNAi recombinant adenoviral expressive vectors specific to glycogen synthase kinase-3beta (GSK-3beta) and to observe its gene knockdown effect on the expression of GSK-3beta, and to explore the effect of Wnt/beta-catenin pathway on the proliferation of human thyrocytes using the RNAi adenovirus vector. METHODS An adenovirus plasmid… (More)

Topics

Cite this paper

@article{Chen2008ConstructionOG, title={[Construction of GSK-3beta-targeting RNAi adenovirus vector and the influence of Wnt/beta-catenin pathway in proliferation of human thyrocytes].}, author={Gang Chen and Lun-pan Mou and Jin Yao and Ting-ting You and Xiao-Yan Shen and Xiang-qing Zhu and Yu-fang Qiao and Miao Lin and Xiao-wen Fang and Xin Zou and Li-xiang Lin}, journal={Zhonghua yi xue za zhi}, year={2008}, volume={88 40}, pages={2821-5} }