[Connection of HindIII-polymorphism in the lipoprotein lipase gene with myocardial infarct and life span in elderly ischemic heart disease patients].

@article{Malygina2001ConnectionOH,
  title={[Connection of HindIII-polymorphism in the lipoprotein lipase gene with myocardial infarct and life span in elderly ischemic heart disease patients].},
  author={Natalia Malygina and A. S. Melent'ev and Irina Kostomarova and I. A. Melent'ev and R T Sa{\'e}gitov and Iu B Smirnova and Ludmila D. Serova},
  journal={Molekuliarnaia biologiia},
  year={2001},
  volume={35 5},
  pages={787-91}
}
Allele and genotype frequencies of the HindIII polymorphism of the lipoprotein lipase (LPL) gene were studied in patients with myocardial infarction (MI) and stable angina of effort (SAE), including long-lived people (over 90). The polymorphism proved to be associated with MI and with the life span, genotype H+/H+ being predisposing to MI and allele H- being protective. The allele and genotype frequencies of long-lived people differed significantly from the Hardy-Weinberg proportions and from… CONTINUE READING

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