Corpus ID: 22428556

[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].

@article{Ji1992ComparisonOA,
  title={[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].},
  author={G. Ji and D. Zhao and D. Q. Liu and B. Sheng},
  journal={Yao xue xue bao = Acta pharmaceutica Sinica},
  year={1992},
  volume={27 6},
  pages={
          407-11
        }
}
The antiarrhythmic actions of 3,6-dimethylamino-dibenzopyridonium edetate (IHC-72), lidocaine (Lid) and verapamil (Ver) on several models Were compared at equitoxic doses (equal fraction of LD50). The action of IHC-72 against aconitine induced arrhythmia was similar to that of Lid but stronger than that of Ver in anesthetized rats. The effect of IHC-72 on ouabain induced arrhythmia was also similar to that of Lid, but weaker than that of Ver in anesthetized guinea pigs. The activity of IHC-72… Expand

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