[Comparative studies in patients with seropositive and seronegative chronic polyarthritis using the solid-phase ELISA test for the determination of rheumatoid factors of classes IgM, IgG and IgA].

@article{Zlabinger1988ComparativeSI,
  title={[Comparative studies in patients with seropositive and seronegative chronic polyarthritis using the solid-phase ELISA test for the determination of rheumatoid factors of classes IgM, IgG and IgA].},
  author={Gerhard J Zlabinger and Hans Broell},
  journal={Zeitschrift fur Rheumatologie},
  year={1988},
  volume={47 2},
  pages={107-12}
}
Sera from patients with definite or classic rheumatoid arthritis (RA) were tested for their reactivity to the Fc fragment of human IgG using a solid phase Elisa with specificity for rheumatoid factors (RF) of classes IgM, IgG and IgA. For all RF classes tested the Elisa was reproducible both within and between different assays. IgM-RF-serum concentrations correlated well to the Waaler Rose titers (r = 0.88, p less than 0.001). No difference in RF-serum concentrations of any Ig class could be… CONTINUE READING