[Comparative sensitivity of the sympathetic and parasympathetic ganglia to ganglionic blockaders].


Pharmacological tests in vitro on the cat isolated superior cervical and ciliary ganglia identified the IEM-1194 as a selective parasympathetic ganglion-blocking agent. The ganglion-blocking activity of this drug was three times as high in parasympathetic ganglion (EC50 = 1.15 +/- 0.34 M/1 x 10(-5)) as in sympathetic one (EC50 = 3.2 +/- 0.2 M/1 x 10(-5)). I… (More)


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