Corpus ID: 22646901

[Combination of cyproterone acetate and natural estrogens in the treatment of hirsutism].

@article{Pugeat1991CombinationOC,
  title={[Combination of cyproterone acetate and natural estrogens in the treatment of hirsutism].},
  author={M. Pugeat and M. Nicolas and H. D{\'e}chaud and M. Elmidani},
  journal={Journal de gynecologie, obstetrique et biologie de la reproduction},
  year={1991},
  volume={20 8},
  pages={
          1057-62
        }
}
The effects of oral administration of cyproterone acetate (CPA) (50 mg) associated with natural estrogens, was investigated in two groups of hirsute women. One group received 17-beta estradiol valerianate (E2) (2 mg) (n = 22) and the other, micronized E2 (2 mg) plus estriol (E3) (1 mg) daily (n = 22) for 21 days every month. After a six month period of treatment, hirsutism improved in 70% of the patients. The more frequent adverse effect was amenorrhea. Except in one, weight gain was prevented… Expand
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