[Clinical usefulness of T-SPOT.TB test for the diagnosis of tuberculosis].

@article{Kim2010ClinicalUO,
  title={[Clinical usefulness of T-SPOT.TB test for the diagnosis of tuberculosis].},
  author={Hyun Soo Kim and Cheol-Hong Kim and Mina Hur and In Gyu Hyun and Min-Jeong Park and Wonkeun Song and Ji Young Park and Hee Jung Kang and Kyu Man Lee},
  journal={The Korean journal of laboratory medicine},
  year={2010},
  volume={30 2},
  pages={
          171-7
        }
}
BACKGROUND Tuberculosis-specific ELISPOT assay (T-SPOT.TB, Oxford Immunotec, UK) is a test that detects interferon-gamma producing T-cells after stimulating patient's lymphocytes with two kinds of tuberculosis-specific antigens (ESAT-6 and CFP-10). We evaluated clinical usefulness of T-SPOT.TB test in Korean adults with intermediate burden of tuberculosis and high rate of BCG vaccination at birth. METHODS T-SPOT.TB test was performed in 79 patients and 64 healthy volunteers and these patients… 
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[Analysis of patients with positive acid-fast bacilli culture and negative T-SPOT.TB results].
TLDR
The results suggest that T-SPOT.TB test is very sensitive for diagnosing active tuberculosis, but MTB infection in immunocompromised patients also has to be considered.
Diagnosis of Mycobacterium tuberculosis
TLDR
An alarming increase in morbidity and mortality highlights the need to strengthen control measures andurate and rapid diagnosis is essential for controlling the disease.
Clinical immunosensing of tuberculosis CFP-10 in patient urine by surface plasmon resonance spectroscopy
The Risk of Tuberculosis in Korean Patients with Inflammatory Bowel Disease Receiving Tumor Necrosis Factor-α Blockers
TLDR
Treatment with TNF-α blockers significantly increased the risk of TB in IBD patients in Korea, and de novo pulmonary TB infection was more prevalent than reactivation of LTBI, suggesting an urgent need for specific recommendations regarding TB monitoring during T NF-α blocker therapy.

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