• Corpus ID: 28441390

[Clinical and socio-medical aspects of long term uricostatic treatment of primary gout (a 5-10 year study)].

@article{Klein1978ClinicalAS,
  title={[Clinical and socio-medical aspects of long term uricostatic treatment of primary gout (a 5-10 year study)].},
  author={G. Klein and Franz Rainer and P Schmid and G. Schneider},
  journal={Zeitschrift fur Rheumatologie},
  year={1978},
  volume={37 5-6},
  pages={
          165-73
        }
}
In 60 patients (48 cases were evaluated) with primary gout a longterm therapy (5--10 years) with Allopurinol was performed. Without treatment 4.4 sudden onsets of gout per patient and year were registrated; under Allopurinol only 0.062 (p less than 0.001) onsets were observed. This resulted in a large decrease in hospitalisation time from 44 days to 0.62 days per patient and year. In the majority of cases involution or diminuation of the tophi was found. In 7 cases of nephrolithiasis no further… 
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British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of gout.
TLDR
Evidence-based guidelines are needed for gout management and prevention based on expert consensus rather than research evidence and audits of practice suggest that treatment is very variable.