[Cleavage of RNA in a hybrid duplex by E. coli ribonuclease H. III. Substrate characteristics of hybrid duplexes of RNA and oligodeoxyribonucleotides containing a bleomycin A5 residue].

@article{Vorobev2002CleavageOR,
  title={[Cleavage of RNA in a hybrid duplex by E. coli ribonuclease H. III. Substrate characteristics of hybrid duplexes of RNA and oligodeoxyribonucleotides containing a bleomycin A5 residue].},
  author={P E Vorob'ev and Dmitrii V Pyshnyi and Eric Wickstrom and V. F. Zarytova},
  journal={Bioorganicheskaia khimiia},
  year={2002},
  volume={28 4},
  pages={332-40}
}
The effect of the bleomycin A5 residue linked to four-, eight-, and twelve-mer oligodeoxyribonucleotides on the substrate properties of their tandem and continuous (with or without unmodified octanucleotide effectors) hybrid duplexes was studied using E. coli RNase H. The bleomycin derivatives of oligodeoxyribonucleotides were shown to form hybrid duplexes… CONTINUE READING