Corpus ID: 37887134

[Characterization of 9 slowly dissociated opioid ligands azabicyclononances compounds to mu, delta, and kappa receptors].

@article{Fan1991CharacterizationO9,
  title={[Characterization of 9 slowly dissociated opioid ligands azabicyclononances compounds to mu, delta, and kappa receptors].},
  author={L. Q. Fan and W. Jin and Z. Chi},
  journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  year={1991},
  volume={12 3},
  pages={
          245-9
        }
}
  • L. Q. Fan, W. Jin, Z. Chi
  • Published 1991
  • Chemistry, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica Sinica
In the receptor binding assay, the relative affinity ratios of P-7548 [3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-propionoxyphenyl)-3- azabicyclo (3,3,1)nonane], P-7556 [3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-benzoyloxyphenyl)-3- azabicyclo(3,3,1)nonane] and P-7618 [3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-[m-(1-cyclopentyl- propionoxyphenyl)]-3-azabicyclo(3,3,1)nonane] were 56:16:1, 1:4:1, and 6:0.2:1 at mu, delta, and kappa sites, respectively. These compounds possessed a tight… Expand