[Characteristics of mutagenesis induced by nitrosomethylurea in a mammalian multilocus system in vitro].

@article{Pashin1987CharacteristicsOM,
  title={[Characteristics of mutagenesis induced by nitrosomethylurea in a mammalian multilocus system in vitro].},
  author={Iu V Pashin and L. E. Sal'nikova and V I Kozachenko},
  journal={Genetika},
  year={1987},
  volume={23 12},
  pages={2268-71}
}
The mutagenic effect of short- and long-term MNU exposition causing alkylation and that combined with carbamoylation, correspondingly, at the four specific gene loci of the CHO-AT3-2 Chinese hamster line was studied. The increase both in MNU mutagenic effects and in the range of induced changes resulted from intensification of carbamoylating processes. True… CONTINUE READING