[Characteristics of hyperthermia-induced apoptotic cell death].

  title={[Characteristics of hyperthermia-induced apoptotic cell death].},
  author={Taku Honma},
  journal={Nihon rinsho. Japanese journal of clinical medicine},
  volume={54 7},
  • Taku Honma
  • Published 1996 in
    Nihon rinsho. Japanese journal of clinical…
Hyperthermia shows considerable promise as a treatment modality for cancer. It is widely accepted that hyperthermia at doses that fall within the therapeutic range triggers cell death by apoptosis in susceptible cell populations, higher heat loads producing necrosis. The hyperthermia-induced apoptosis is characterized both by its distinctive ultrastructural features and by the occurrence of internucleosomal DNA cleavage. The thermosensitivity to apoptotic induction varies enormously from cell… CONTINUE READING

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