Corpus ID: 27450978

[Changes of spleen cytokines in mice immunized with recombinant Bb-Eg95-EgA31 vaccine against Echinococcus granulosus].

@article{Zhou2010ChangesOS,
  title={[Changes of spleen cytokines in mice immunized with recombinant Bb-Eg95-EgA31 vaccine against Echinococcus granulosus].},
  author={Bi-ying Zhou and Ya-tang Chen and Wen-gui Li and Mei Yang},
  journal={Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology \& parasitic diseases},
  year={2010},
  volume={28 4},
  pages={
          268-72
        }
}
  • Bi-ying Zhou, Ya-tang Chen, +1 author Mei Yang
  • Published 2010
  • Biology, Medicine
  • Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases
OBJECTIVE To investigate the level of cytokines in spleen from mice immunized with recombinant Bifidobacteria bifidum(Bb)-Eg95-EgA31 vaccine of Echinococcus granulosus (Eg) and challenged with Eg protoscoleces. METHODS 56 female BALB/c mice were randomly divided into 7 groups: Recombinant Bb-Eg9S-95-EgA31 vaccine subcutaneous injection (group A), intramuscular injection (B), intranasal immunization (C), oral administration (D), blank vector control (E), Bb control (F) and MRS control (G… Expand
1 Citations
Current situation and future prospects of Echinococcus granulosus vaccine candidates: a systematic review.
TLDR
The data demonstrated that DNA vaccines with antigen B and recombinant protein vaccines based on EG95 antigen have the best results and elicited protective immune responses. Expand