[Changes of N-methyl-D-aspartate receptor in spinal cord after trauma].

N-methyl-D-aspartate (NMDA) receptor-mediated events have implicated in the pathophysiology of posttraumatic spinal cord injury. In the present study, [3H] CPP was used as ligand to analyse the changes in NMDA receptor-binding sites in synaptic plasma membranes (SPM) isolated from rat spinal cord after impact trauma at T10. Radio-binding assays of [3H] CPP… CONTINUE READING