[Changes in cell cycle of human hepatoma xenograft in nude mice after irradiation].

@article{Cao1990ChangesIC,
  title={[Changes in cell cycle of human hepatoma xenograft in nude mice after irradiation].},
  author={Shi Larry Cao},
  journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]},
  year={1990},
  volume={12 1},
  pages={
          12-4
        }
}
  • Shi Larry Cao
  • Published in
    Zhonghua zhong liu za zhi [Chinese journal of…
    1990
Cell kinetics in human hepatoma xenograft in nude mice after gamma irradiation was studied using flow cytometry (FCM) method and the changes of AFP in the xenograft were measured by radioimmunological assay. After 10 Gy irradiation, a marked tumor growth delay for 10 days was observed. Cell cycle analysis revealed an acute but temporary block of cell cycling at G2. About 58% cells were in the G2 phase lasting for 90 hours post-irradiation. A concomitant decrease in serum AFP determined by RIA… CONTINUE READING