[Centre de référence sur les agents tératogènes (CRAT): a pioneer center].

  title={[Centre de r{\'e}f{\'e}rence sur les agents t{\'e}ratog{\`e}nes (CRAT): a pioneer center].},
  author={Elisabeth Elefant and Catherine Vauzelle and Delphine Beghin},
  volume={69 1},
Le Centre de référence sur les agents tératogènes (CRAT), founded in 1975, is the first national and international public organization especially involved in the problem of drugs during pregnancy, and during this period of time has been responsible for many initiatives in this field: health care providers information and counsel service, innovating risk assessment methodology, new method for clinical data collection leading to a database including more than 50 000 exposed pregnancies… 

The importance of pharmacoepidemiology in pregnancy-implications for safety

The diversity of data sources and approaches of pharmacoepidemiologic studies, the implementation of international networks as well as the improvement of adverse signal detection are the keystones of such an evaluation.

Emerging Role of Zika Virus in Adverse Fetal and Neonatal Outcomes

It is currently difficult to assess the magnitude of increase of microcephaly prevalence in Brazil, as well as the role of other factors in the development of congenital neurological conditions, and studies are urgently needed to answer the questions surrounding ZIKV.

Mefloquine safety and tolerability in pregnancy: a systematic literature review

There are no indications that MQ use during pregnancy carries an increased risk for the foetus and Ideally, the use of MQ to prevent malaria should be based on a risk-benefit analysis of adverse effects against the risk of acquiring the infection.

Traitements des mycoses vulvo-vaginales aiguës et récidivantes

Cependant, en l'absence d'etudes cliniques approfondies sur les plantes et huiles essentielles antifongiques, le pharmacien doit rester vigilant and conseilleravec prudence ces traitements a base of plantes.

Microbiological and molecular screening of Candida spp. isolated from genital tract of asymptomatic pregnant women.

Monitoring of vaginal Candida colonization before the third trimester of pregnancy, that could reduce congenitalcandida colonization and risk of pregnancy complications, is recommended.

Safety of first year vaccination in children born to mothers with inflammatory bowel disease and exposed in utero to anti‐TNFα agents: a French nationwide population‐based cohort

Children born to mothers with IBD may be exposed to anti‐TNFα agents antenatally. Current European guidelines recommend postponing live vaccines until after 6 months of life in this population. Data

Efficacy of shared decision-making on treatment adherence of patients with bipolar disorder: a cluster randomized trial (ShareD-BD)

This will be the first study evaluating the effect of an SDM intervention on patient adherence in bipolar disorder (BD), and proposes the development of an evidence-based tool that should help patients and clinicians to initiate discussions regarding the use of BD treatment.

Le choix thérapeutique : médicaments du psoriasis et grossesse avant, pendant et après la grossesse

  • A. Villani
  • Medicine
    European Journal of Dermatology
  • 2020
Les données concernant les biothérapies prises en cours de grossesse sont rassurantes, le principal risque étant l’immunodépression du nouveau-né en cas of maintien du traitement.

Grossesse et psoriasis : le point de vue du gynécologue-obstétricien

Une consultation préconceptionnelle auprès d’un gynécologue-obstétricien, spécialiste des grossesses pathologiques, est fortement recommandée pour un premier contact and expliquer le suivi de the grossesse.


Teratogenic Agent Information Centre: fifteen years of counseling and pregnancy follow-up.

The Teratogenic Agent Information Centre was set up 15 years ago in response to a growing demand from a medical profession struggling to cope with the problem of teratogenic risk. Our goal was to