[Catalytic biotransformation of physiologically active 1-methyl-4- aryl-1,2,3,6-tetrahydropyridines under the action of monoaminooxidase].

@article{Bachurin1989CatalyticBO,
  title={[Catalytic biotransformation of physiologically active 1-methyl-4- aryl-1,2,3,6-tetrahydropyridines under the action of monoaminooxidase].},
  author={Sergey Bachurin and Sergey O Sablin and G V Grishina and E L Gaĭdarova and D G Dubova},
  journal={Bioorganicheskaia khimiia},
  year={1989},
  volume={15 5},
  pages={620-6}
}
Kinetics of monoamine oxidase (MAO) catalyzed dehydrogenation of neurotropic analogues of biogenic monoamines in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine series were studied. It is shown that methyl substitution in the phenyl ring increases significantly the enzyme-substrate affinity, but the substituent's effect on the catalytic stage largely… CONTINUE READING