[Calcium regulation by troponin and its genetic disorder in striated muscle contraction].

  • Iwao Ohtsuki
  • Published 2002 in
    Nihon yakurigaku zasshi. Folia pharmacologica…


Contraction of skeletal and cardiac muscles is regulated by Ca2+ through specific Ca(2+)-regulatory proteins, troponin and tropomyosin, located in the thin filament. Troponin is a Ca2+ receptive protein consisting of three differet components, troponins C, I, and T. The essential mechanisms of Ca(2+)-regulation are the inhibition of contractile interaction… (More)


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