[Calcium channel blockers pharmacology and their use as tocolytics].


Nifedipine and nicardipine are both calcium channel inhibitors, used off-label as tocolytics in preterm labour. Their use is related to their relaxing effects on uterin muscle by L-type voltage dependent calcium channels blockade. This article describes pharmacological effects, pharmacokinetics properties and tolerance of these drugs. It also discusses… (More)
DOI: 10.1016/j.jgyn.2014.12.010