[Calcium and lipid peroxidation in the heart mitochondrial and microsomal membranes].

@article{Kagan1983CalciumAL,
  title={[Calcium and lipid peroxidation in the heart mitochondrial and microsomal membranes].},
  author={Valerian E Kagan and V. M. Savov and Vladimir Didenko and I. V. Arkhipenko and Felix Z. Meerson},
  journal={Biulleten' eksperimental'noi biologii i meditsiny},
  year={1983},
  volume={95 4},
  pages={46-8}
}
Effect of the lipid peroxidation (LP) on the Ca2+-transport and the effect of different Ca2+-concentrations on the LP activation were studied in microsomes and mitochondria of the heart. A slight accumulation of LP-products in the microsomal fraction results in a complete inhibition of the membrane calcium-transport activity. Preliminary administration of antioxidants (4-methyl 2,6-ditretbutylphenol and alpha-tocopherol) prevents both the accumulation of LP-products and damage of the Ca2… CONTINUE READING
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