• Corpus ID: 37169262

[Calcification of thrombus associated with central venous catheter: unusual complication].

@article{Dounas2000CalcificationOT,
  title={[Calcification of thrombus associated with central venous catheter: unusual complication].},
  author={Mokhtar Dounas and Akira Yamami and P Peillon and P Martinais and F Angenard},
  journal={Annales francaises d'anesthesie et de reanimation},
  year={2000},
  volume={19 9},
  pages={
          684-7
        }
}

• M. Dounas, A. Yamami, +2 authors F. Angenard
• Published 2000
• Medicine
• Annales francaises d'anesthesie et de reanimation

Thrombosis originating from the tip of central venous catheter is a well known complication. The calcification of such a thrombus is very rare. Until now, only two cases had been described with long-term indwelling central venous catheters used for total parenteral nutrition. We report the first case of a calcified thrombus occurred during a short-term central venous catheterisation. The presumptive mechanism of thrombus calcification is precipitation of calcium salts and its deposition on a pre-existent thrombus. In total parenteral nutrition the mechanism of calcification seems to be multifactorial. Thus, the precipitation of calcium phosphate is increased by the following factors: higher calcium and phosphate concentrations, the use of calcium chloride instead of calcium gluconate, lower pH solutions, slow infusion rate.