[Ca2+]i signalling in sperm — making the most of what you've got

@article{Publicover2007Ca2iSI,
  title={[Ca2+]i signalling in sperm — making the most of what you've got},
  author={Stephen J. Publicover and Claire V. Harper and Christopher L. R. Barratt},
  journal={Nature Cell Biology},
  year={2007},
  volume={9},
  pages={235-242}
}
Thanks to a worrying decrease in male fertility, understanding how sperm 'work' is a matter both of interest and great importance. Sperm of all animals detect various environmental cues. The 'behavioural' and physiological responses of sperm must be specific, appropriate and correctly timed. Strangely, in a cell with few organelles and minimal cytoplasmic volume, internal Ca2+ concentration, [Ca2+]i, regulates almost all these activities. How does such a simple cell achieve this — and is it as… CONTINUE READING

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