[C677T genetic polymorphism of methylenetetrahydrofolate reductase in premature coronary heart disease].

Abstract

OBJECTIVE Methylenetetrahydrofolate reductase (MTHFR) is an important factor responsible for hyperhomocysteinemia. The relation of MTHFR gene C677T polymorphism and premature coronary heart disease was studied. METHODS MTHFR C677T genetic polymorphisms in 67 patients with premature coronary heart disease were detected by PCR-RFLP technique. RESULTS In… (More)

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