[Bone marrow mesenchymal stem cell-derived exosome protects kidney against ischemia reperfusion injury in rats].

@article{Wang2014BoneMM,
  title={[Bone marrow mesenchymal stem cell-derived exosome protects kidney against ischemia reperfusion injury in rats].},
  author={Rulin Wang and Miao Chu Lin and Li-ping Li and Long Li and Guisheng Qi and Ruiming Rong and Ming Xu and Tongyu Zhu},
  journal={Zhonghua yi xue za zhi},
  year={2014},
  volume={94 42},
  pages={3298-303}
}
OBJECTIVE To explore the protective effects and mechanism of exosomes derived from bone marrow mesenchymal stem cells (BM-MSC) on ischemia reperfusion injury (IRI) in rats. METHODS Rat-MSC were isolated, cultured and identified.Exosome was extracted from BM-MSC and observed under transmission electron microscope (TEM). The expression of surface molecular marker CD63 was tested by flow cytometry. Male Sprague-Dawley rats were randomly grouped into sham-operated (Sham), ischemia reperfusion (IR… CONTINUE READING