[Biophysical Characterization of Biopharmaceuticals, Including Antibody Drugs].

@article{Uchiyama2016BiophysicalCO,
  title={[Biophysical Characterization of Biopharmaceuticals, Including Antibody Drugs].},
  author={Susumu Uchiyama},
  journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan},
  year={2016},
  volume={136 3},
  pages={
          443-8
        }
}
Biopharmaceuticals, including antibody drugs, are now popular because of their high specificity with low adverse effects, especially in the treatment of cancer and autoimmune diseases. However, because the active pharmaceutical ingredients of biopharmaceuticals are proteins, biophysical characterization of these therapeutic proteins should be required. In this manuscript, methods of chemical and physical characterization of therapeutic proteins are described. In terms of chemical… CONTINUE READING