[Bile acids in the therapy of chronic liver diseases].

  title={[Bile acids in the therapy of chronic liver diseases].},
  author={Marco Sperandeo and Antonio Varriale and Giuseppe Sperandeo and Stefano Carughi and Luca Lucentini},
  journal={Recenti progressi in medicina},
  volume={84 3},
In the last 10 years, interest about the employment of bile acids, especially of ursodeoxycholic acid (UDCA), in the treatment of chronic liver diseases has increased. The mechanism has not been completely explained yet, but this agent has been thought to act mainly by making bile less toxic for the liver cells, reducing the fraction of hydrophobic detergent bile acids. UDCA is effective in decreasing serum concentrations of liver enzymes in chronic liver diseases, especially in those… CONTINUE READING