[Autocrine regulation of hexokinase activity by HB-EGF in mesangial cells].

OBJECTIVE To investigate the influence of heparin-binding epidermal growth factor-like growth factor (HB-EFG) on the activity of hexokinases (HKs) in mesangial cells stimulated by phobal ester. METHODS SV40MES13 mesangial cell line was used as cell model and the total activity of HKs was measured by using standard G-6-PDH-coupled assay. Exogenous HB-EGF… CONTINUE READING