[Association of the CYP1B1 gene polymorphism with susceptibility to endometriosis].
@article{Li2009AssociationOT, title={[Association of the CYP1B1 gene polymorphism with susceptibility to endometriosis].}, author={Yi-ge Li and Xin Wang}, journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics}, year={2009}, volume={26 1}, pages={ 66-9 } }
- Published 2009 in Zhonghua yi xue yi chuan xue za zhi = Zhonghua…
DOI:10.3760/cma.j.issn.1003-9406.2009.01.015
OBJECTIVE
To study the association between gene polymorphisms of cytochrome P450 1B1 (CYP1B1) in exon 2 codon 119 (G-T) and exon 3 codon 432 (C-G) and the susceptibility to endometriosis.
METHODS
Allele-specific polymerase chain reaction was used to analyze the gene polymorphisms in 55 cases of endometriosis and 45 cases of normal controls.
RESULTS
The frequencies of alleles G and T in codon 119 G/T of CYP1B1 gene showed a significant difference between the endometriosis group and the… CONTINUE READING