[Association of hOGG1 genotype with life style and oxidative DNA damage in five ethnic populations in China].

Abstract

OBJECTIVE To assess the natural variation of hOGG1 gene and the gene-environmental interactions. METHODS The hOGG1 codon 326 polymorphism and urinary 8-OHdG levels were investigated in a large sample of healthy individuals (n = 953) from five ethnic populations in China by using PCR-RFLP and HPLC-ECD. Life style parameters were obtained through a… (More)

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