[Association of abnormal lipid metabolism with INSIG2 gene variant in overweight and obese children].


OBJECTIVE To study the relationship between insulin induced gene 2 (INSIG2) variant and obesity or lipid metabolism in Chinese children and adolescents. METHODS A total number of 2030 school students at the age from 7 to 18 years were selected in Beijing. Physical indicators, serum lipids and the rs13428113 polymorphism in INSIG2 gene were examined for… (More)