[Association of TNFA polymorphisms with the outcomes of HBV infection].

  title={[Association of TNFA polymorphisms with the outcomes of HBV infection].},
  author={Ying Liu and Xin-hui Guo and Te Du and Jun-hong Li and Xi-lin Zhu and Ji-rong Gao and Liang-ping Lu and Chun-yan Gou and Zhuo Li and Hui Li},
  journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics},
  volume={22 4},
OBJECTIVE To explore whether the TNFA promoter single nucleotide polymorphisms (SNPs) are associated with the outcomes of hepatitis B virus(HBV) infection in Chinese Han population. METHODS One hundred and forty-eight self-limited HBV infection subjects and 207 chronic hepatitis B patients were recruited. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and sequence specific primer-PCR(PCR-SSP) were used to detect the SNPs of five sites in TNFA promoter (-238G/A… CONTINUE READING