[Association of CMA1 gene tag single nucleotide polymorphisms with essential hypertension in Yi population from Yunnan].

@article{Wu2014AssociationOC,
  title={[Association of CMA1 gene tag single nucleotide polymorphisms with essential hypertension in Yi population from Yunnan].},
  author={Yanrui Wu and Qian Li and Ke Yang and Chunjie Xiao},
  journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics},
  year={2014},
  volume={31 4},
  pages={
          449-54
        }
}
OBJECTIVE To assess the association of tag single nucleotide polymorphisms (tag SNPs) of chymase gene (CMA1) with essential hypertension in Yi population from Yunnan, China. METHODS A case-control study was carried out. Four tag SNPs(rs1956921, rs1800876, rs5244 and rs1885108) were genotyped in 303 patients with essential hypertension and 312 healthy controls using polymerase chain reaction - restriction fragment length polymorphism(PCR-RFLP) method. RESULTS No significant difference in… CONTINUE READING