[Association between mood characteristics and polymorphisms of glial cell line-derived neurotrophic factor (GNDF) in patients with depression].

@article{Kotyuk2013AssociationBM,
  title={[Association between mood characteristics and polymorphisms of glial cell line-derived neurotrophic factor (GNDF) in patients with depression].},
  author={Eszter Kotyuk and N{\'o}ra N{\'e}meth and Zsuzsa Halmai and Gabor Faludi and M{\'a}ria Sasv{\'a}ri-Sz{\'e}kely and Anna Sz{\'e}kely},
  journal={Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology},
  year={2013},
  volume={15 2},
  pages={63-72}
}
Glial cell line-derived neurotrophic factor (GNDF) plays an important role in the development and synaptic plasticity of dopaminergic neurons, thus it could be an important therapeutic factor in Parkinson's disease. Results from candidate gene studies of GDNF in psychiatric disorders are contradictory. Moreover, the possible association between GDNF polymorphisms and major- or bipolar depression has not been studied to date. Recently, our research group has published an association between two… CONTINUE READING