Corpus ID: 49208335

[Association between SLC22A12 rs1529909 and rs7929627 polymorphism and hyperuricemia].

@article{Zhang2017AssociationBS,
  title={[Association between SLC22A12 rs1529909 and rs7929627 polymorphism and hyperuricemia].},
  author={Yadi Zhang and Fandi Zhang and Li Zhao and Jian-fang Du and Yun Wang and Zhongqin Guo},
  journal={Wei sheng yan jiu = Journal of hygiene research},
  year={2017},
  volume={46 4},
  pages={
          589-594
        }
}
OBJECTIVE To investigate the relationship between SLC22A12 gene rs1529909 and rs7929627 polymorphism and hyperuricemia of residents in Yinchuan, Ningxia province. METHODS Through retrospective analysis in healthy subjects from April to November in 2014, 365 patients with hyperuricemia were selected. 1∶ 1 matched casecontrol study was carried out, matched with age( ± 5 years old), gender, race, and selected 365 people with normal serum uric acid levels as the control group. All subjects were… Expand
1 Citations
Relationship between URAT1 Gene Polymorphism and Uric Acid-Lowering Effect of Losartan in Hypertensive Patients with Hyperuricemia
  • Y. Wang, Y. C. Fan, +6 authors X. Bai
  • Medicine
  • Indian Journal of Pharmaceutical Sciences
  • 2020
TLDR
The rs7929627, rs75786299, and rs3825017 of the URAT1 gene could affect the uric acid-lowering effect of losartan and the levels of uric Acid and creatinine in hypertensive patients with hyperuricemia were significantly lower than those with TT genotype. Expand