[Assay of cardiotonic steroids based on a 2-compartment model].

  • Yumi Katano
  • Published 1975 in
    Nihon yakurigaku zasshi. Folia pharmacologica…
In an attempt to develop an assay method for cardiotonic steroids (CS), a two compartment model was applied to the whole dog. As representative CS, g-strophanthin, digoxin and digoxigenin were infused continuously to the animal, and the minimal cardiotonic, irregularity and lethal doses were determined, together with indices K1 and K2, representing the rate… CONTINUE READING