[Application of multiplex PCR in genotyping of hepatitis B virus prevailing in Guangdong Province of China].


OBJECTIVE To establish a convenient method for the genotyping of hepatitis B virus (HBV) using multiplex PCR. METHOD Based on the alignment of 114 complete nucleotide sequences of HBV DNA belonging to different genotypes, acquired from the GenBank, genotype-specific sequences were identified according to which 6 pairs of primers were designed… (More)